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\u8fd1\u65e5\u5317\u4eac\u5927\u5b66\u56e2\u961f\u53d1\u5e03\u5728\u300aPharmacological Research\u300b\u671f\u520a\u4e0a\u7684\u4e00\u9879\u91cd\u78c5\u7814\u7a76\u7ed3\u679c\u8868\u660e\u4f20\u7edf\u751f\u53d1\u4e2d\u836f\u4f55\u9996\u4e4c\u4e2d\u7684\u690d\u7269\u5916\u6ccc\u4f53\u6837\u7eb3\u7c73\u9897\u7c92\uff08PMENs\uff09\u80fd\u591f\u4f5c\u4e3a\u5929\u7136\u8f7d\u4f53\uff0c\u5b9e\u73b0\u8de8\u7269\u79cd\u57fa\u56e0\u8c03\u63a7\uff0c\u6216\u8bb8\u80fd\u4e3a\u6cbb\u7597AGA\u5f00\u8f9f\u4e00\u6761\u5168\u65b0\u7684\u8def\u5f84\u3002<\/p>\n\n\n\n

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\"\"<\/figure>\n\n\n\n

\u56fe1<\/p>\n\n\n\n

    \n
  1. \u6f5c\u5165\u7ec6\u80de<\/strong>\uff1a PMENs\u901a\u8fc7\u5c0f\u7a9d\u86cb\u767d\u548c\u786b\u9178\u4e59\u9170\u809d\u7d20\u86cb\u767d\u805a\u7cd6\uff08HSPG\uff09\u4ecb\u5bfc\u7684\u5185\u541e\u9014\u5f84\u8fdb\u5165\u7ec6\u80de\u3002\u5b9e\u9a8c\u8868\u660e\uff0c\u4f7f\u7528\u7279\u5b9a\u6291\u5236\u5242\u963b\u65ad\u8be5\u9014\u5f84\u540e\uff0cPMENs\u7684\u7ec6\u80de\u6444\u53d6\u7387\u53ef\u88ab\u6291\u5236\u9ad8\u8fbe86.85%\uff0c\u5c55\u73b0\u4e86\u5176\u9ad8\u6548\u7684\u7ec4\u7ec7\u9776\u5411\u6027\u3002\u7531\u6b64\u53ef\u9ad8\u6548\u201c\u6f5c\u5165\u201d\u4eba\u7c7b\u6bdb\u56ca\u771f\u76ae\u4e73\u5934\u7ec6\u80de\u3002<\/li>\n\n\n\n
  2. \u9776\u5411\u6c89\u9ed8<\/strong>\uff1a\u8fd9\u662f\u673a\u5236\u7684\u6838\u5fc3\u3002\u9ad8\u901a\u91cf\u6d4b\u5e8f\u53d1\u73b0PMENs\u4e2d\u5bcc\u542b\u7684aof-miR168a\u548cosa-miR164a\u4e0e\u4eba\u7c7bAR\u57fa\u56e03’\u975e\u7ffb\u8bd1\u533a\u5b58\u5728\u9ad8\u5ea6\u4e92\u8865\u6027\uff08\u5982\u56fe2\uff09\uff0c\u9884\u793a\u5f3a\u5927\u7684\u7ed3\u5408\u6f5c\u529b\u3002\u00a0aof-miR168a\u00a0\u548c\u00a0osa-miR164a\u80fd\u50cf\u201c\u7cbe\u786e\u5236\u5bfc\u5bfc\u5f39\u201d\u4e00\u6837\uff0c\u76f4\u63a5\u627e\u5230\u5e76\u7ed3\u5408\u5bfc\u81f4AGA\u7684\u6838\u5fc3\u7978\u9996\u2014\u2014\u96c4\u6fc0\u7d20\u53d7\u4f53\uff08AR\uff09\u57fa\u56e0\u76843’\u975e\u7ffb\u8bd1\u533a\uff083’UTR\uff09\u3002\u8fd9\u79cd\u7ed3\u5408\u5bfc\u81f4AR\u7684mRNA\u88ab\u964d\u89e3\uff0c\u4ece\u6e90\u5934\u4e0a\u51cf\u5c11\u4e86\u201c\u81f4\u75c5\u6307\u6325\u5b98\u201d\uff08AR\u86cb\u767d\uff09\u7684\u6570\u91cf\u3002\u5b9e\u9a8c\u8bc1\u5b9e\uff0cPMENs\u5904\u7406\u53ef\u4f7f\u6bdb\u56ca\u7ec6\u80de\u4e2dAR\u86cb\u767d\u6c34\u5e73\u6700\u9ad8\u4e0b\u964d23.2%\u3002<\/li>\n<\/ol>\n\n\n\n
    \"\"<\/figure>\n\n\n\n

    \u56fe2<\/p>\n\n\n\n

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    <\/p>\n\n\n\n

    <\/div>\n\n\n\n

    \u53c2\u8003\u6587\u732e\uff1a<\/p>\n\n\n\n

      \n
    1. Li S, Zhang Y, Liu X, et al. Cross-kingdom delivery and putative gene modulation of androgen pathways by plant-derived exosome-like nanoparticles from polygoni multiflori radix promotes hair growth via miRNA cargo. Pharmacological Research, 2025, 222: 108033.<\/li>\n<\/ol>\n\n\n\n

      <\/p>\n\n\n\n

      \n\n\n\n
      <\/div>\n\n\n\n

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